Crohn's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Crohn's Disease, including details on symptoms, diagnosis, treatment, causes, medication.

Concurrent development of Crohn disease and myelodysplastic syndrome in a child: case report and literature review.

Nahas SC, Nahas CS, Marques CF, Borba MR, Helito AS, Odoni V

Department of Gastroenterology-Digestive Surgery Division, Hospital das Clínicas, Medical School, University of São Paulo, São Paulo, Brazil. caionahas@uol.com.br

A small number of cases of Crohn disease associated with myelodysplastic syndromes or leukemia have been reported in adults in the last 25 years in the English-language medical literature. The authors report a case of a 9-year-old boy who developed Crohn disease and myelodysplastic syndrome concurrently. Analysis of his bone marrow showed a chromosome 20 abnormality. Although chromosome 20 abnormalities have been reported in a minority of these patients, the significance of this association remains unclear at the present time.

Published 19 July 2006 in Pediatr Hematol Oncol, 23(6): 477-83.
Full-text of this article is available online (may require subscription).

© 2004-2008 Crohn's Disease Research Today. All Rights Reserved.